Birth Defect Gene Isolated

Posted on August 17, 2009 at 8:09pm by

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Newswise reports that researchers from the University of Chicago, University of Alberta, and several other institutions have isolated the gene involved with a common birth defect.

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Dinner at Eight rip Intruder full movie Their study was published in the September issue of Nature and Genetics and says that patients lacking the FOXC1 gene (approximately 1 in 5,000 births) may suffer Dandy-Walker malformation. Dandy-Walker malformation (DWM) is a brain defect that causes movement and coordination disorders as well as fluid buildup around the brain. Children born with DWM require extensive medical treatment.

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The FOXC1 gene acts as a regulator in the brain, helping all parts form properly. Its role with DWM was discovered when researchers found that the brain of a mouse lacking the gene had serious malformations. Researchers then applied their hypothesis to humans, searching for patients lacking the FOXC1 gene who suffered from DWM and found a considerable number of matches.

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